The impact on the variant on RNA or protein perform, determined by experimental evidence from submitters.
This value is calculated by NCBI based on details from submitters. Read through our regulations for calculating the critique status. The volume of submissions which lead to this overview status is demonstrated in parentheses.
There is absolutely no useful proof in ClinVar for this variation. When you have generated functional information for this variation, make sure you take into account distributing that information to ClinVar.
This column involves more information supporting the classification, including citations, the touch upon classification, and in depth proof offered as observations from the variant via the submitter.
The condition to the classification, provided by the submitter for this submitted (SCV) report. This column also includes the afflicted position and allele origin of individuals noticed with this particular variant.
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There aren't any citations for germline classification of this variant in ClinVar. If you understand of citations for this variation, remember to take into account distributing that details to ClinVar.
The publishing Group for this submitted (SCV) document. This column also includes the SCV accession and Model quantity, the day this SCV initial appeared in ClinVar, as well as date this SCV was last up-to-date in ClinVar.
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The number of variants in ClinVar for this gene, including smaller sized variants within the gene and bigger CNVs that overlap or thoroughly comprise the gene.
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Stars depict the critique standing, or the level of overview supporting the submitted (SCV) history. This worth is calculated by NCBI determined by knowledge with the submitter.